19 of the Russian's 21 titles have been won on hard surfaces
A comeback Medvedev won his initial trophy for over two years with victory over Corentin Moutet in the tournament final.
Medvedev, a ex- top-ranked player, has endured a difficult year, achieving just one match at the Grand Slams and undergoing a difficult moment at the New York tournament.
His unpredictability on the professional circuit - and difficulties with his serving in especial - led to him dropping out of the elite rankings and finally separating with long-time trainer his previous coach.
Presently working with Johansson and Goetzke, Medvedev has consistently progressed in the last few weeks - climaxing in a closely contested competitive triumph over challenger Moutet.
It is his initial title after the Italian tournament and first on a hard surface after spring of the previous year.
Success also signifies the Russian has won twenty-one victories at 21 distinct tournaments.
"It's the first time I am participating in a event with my children together, so to get a trophy is especially meaningful," commented ranked player Medvedev.
"This title is in honour of my second daughter Victoria, because the maiden victory I won when my child Alisa was born was for her."
The athlete, the former major winner, had lost his previous six finals, including in Halle earlier this year.
Medvedev's counter-punching approach and recurring reactions on the playing surface had prompted commentators to question if his skill to perform at the highest level was finished.
However the player has altered his approach in recent weeks, striving to come to the net and perform assertively, backed up by an better service.
The champion fought back from a deficit in the opening set against the challenging Moutet, securing 4 of the final five games to take the lead.
Both players traded break points in the following set before the challenger, striving for his maiden tour championship, seized the initiative to push for a third set.
Moutet rescued 4 early-game break points in a competitive third set before Medvedev broke to 15 to serve for the match.
Suitably, he earned the win with a rally at the net, with his opponent failing to control a volley after over two and a half hours.